14.04.2017

Zaluvida: The “Tesla” of pharmaceutical companies becomes a new collaborative partner of ATMOS

Maria Dietrich Maria Dietrich

Zaluvida: The “Tesla” of pharmaceutical companies becomes a new collaborative partner of ATMOS

ATMOS is a grand vision, the likes of which he has never seen before but always missed – that is how Christoph Staeuble, Group CEO of Zaluvida, summarizes his impression after a visit in Linz. Considered the “Tesla” of pharmaceutical companies, the global life-science group is delighted that a dark disease such as mucoviscidosis is being countered with this bright, positive and colorful vision, which the group absolutely wants to be a part of. Working with ATMOS, the goal of getting a handle on the disease in ten years could actually be undercut. Because apparently they can plant a seed for change against mucoviscidosis – namely garlic. Zaluvida’s innovative approach uses a special molecule from this plant.

The extraordinary vision of ATMOS – a biomechanical temple of the muses designed by Coop Himmelb(l)au and initiated by Chris Müller – was presented to the public in Vienna in mid-February. The Selfness Resort is conceived as a source of inspiration for the creative industries while also offering a retreat for mucoviscidosis patients and their relatives, housing research institutions at the same time.

The international reports about ATMOS also drew the attention of the life-science group Zaluvida. Together with its subsidiary Neem Biotech, the Switzerland-based company visited Linz. Chris Müller, who is the father of a child with mucoviscidosis, was not the only one to feel very positive about the scientists’ forecasts.

“We will take the cell phone away from the bacteria.”

A major problem caused by mucoviscidosis is the viscous mucous in the lung. This is where bacteria settle and form a biofilm, beneath which – like a blanket – they entrench themselves and cause terrible inflammations without any resistance. “The patient must take antibiotics by the pounds to first break through the biofilm and then fight the bacteria,” explains Christoph Staeuble, Group CEO Zaluvida.

“We have now opted for an innovative approach which has never been seen before in traditional medicine. These bacteria communicate with each other and attack jointly. We disrupt this and basically take away their cell phones, preventing them from constructing the biofilm. This doesn’t mean that we are repairing the genetic defect, but we are reducing its effects, because by using our active substance, the often severe and sometimes even fatal lung infections of mucoviscidosis patients can be treated much more effectively.”

Dr. Michael Graz, Managing Director of Neem Biotech, adds: “The communication of the bacteria is chemical. We are interfering with this signal. To this end, we are working with a molecule which also occurs in garlic preparations and which can now, with a special technology from Neem Biotech, also be produced in a commercial scope. Presumably this will first appear on the European and American market as a powder for inhalation. We have to get directly into the lung and inhalation is a good method which mucoviscidosis patients are used to. We are working on the development of three generations of our medication. But what I can already promise: less infections, less inflammations in the lung and fewer hospital stays.”

The price of waiting is far too high!

When asked which obstacles might still prevent the introduction of the compounds, Staeuble says: “Nothing!” He is only concerned about the length of time. “Every day on which someone has to suffer is one day too many. The price of waiting is far too high. But legislators are used to administer things that take ten, 15 or 20 years and don’t know how to handle these kinds of innovations. There are numerous innovative pharmaceutical companies in the United States, but in Europe there are just three of these so-called unicorns.”

Matthias Miller, Chief Scientific Officer, explains how the approval process will continue: “The next step is to bring this product into the clinical phase. We networked around the globe with mucoviscidosis associations, medical specialists, practitioners, focus centers, affected persons, etc. It’s important to make the authorities aware of the importance and urgency in a joint effort. This often happens much faster in the United States; they are more optimistic. In Europe, you first see difficulties, which is why it is very important to be in a constant dialog with the political level as well. We have a first approach here, which doesn’t fit into the traditional check lists and is therefore more difficult for the authorities to handle.”

A touch of color for ATMOS

Zaluvida is considered the “Tesla” among pharmaceutical companies. Its global orientation lets the company structure function like a worldwide relationship network. Big dreams, unusual combinations and diversity are success factors for the life-science group. The idea of ATMOS took them by surprise.

“Here a dark illness is countered with a brightly radiant, positive and colorful vision. These people have spent enough time in a hospital and the immediately relevant topics are well-covered. The really grandiose plan – which is how I see ATMOS – was still missing. This inspires me and motivates me to take it up another notch,” says Staeuble. He firmly believes that the future lies in ecologies such as they are envisioned for ATMOS. “They attract like-minded spirits and can inspire technologies far beyond the traditional areas.” Dr. Graz was also surprised by the approach: “As a scientist in a lab, you constantly think of the patient, but he isn’t physically there. ATMOS merges research with the social aspect, which often doesn’t go together. I find this idea extraordinarily inspiring! I think it will become reality very soon and hope that we can participate!”

startUPtown ATMOS unites personal environments

The results of Zaluvida’s research give rise to great hope that the genetic defect can soon be controlled to the point where mucoviscidosis patients can lead a mostly unimpeded life. The prototype of a Stadt-up would thus have the kind of success that isn’t exclusively limited to the illness: “ATMOS is a startUPtown in which – to paraphrase Aristotle – economizing is not an end in itself,” Chris Müller explains.

“The ecology you find at ATMOS is the prototype of new economic practices. This is how we are creating a positive design for an increasingly massive erosion of the boundaries of personal environments. Working, living, thinking, building, starting families, having leisure time – the worlds start to blur and boundaries become worn out – through new communication tools, various concepts of life, other production methods and supply chains. Compatibility is one of the greatest challenges of the 21st century, which has been boosted even further by digitization. ATMOS merges things that didn’t fit together in the old patterns of thinking. What was considered separately is combined in a new way, which is the breeding ground for innovation and makes ATMOS the headwaters of inspiration.”

About Zaluvida

Zaluvida is a globally operating life-science company which strives to develop exceptional health products. It is based in Switzerland and has branches in Germany, Wales, the Netherlands, United States and Malaysia. By using unique bioactive compounds and insights from nature, Zaluvida has become a pioneer in therapies and procedures in the areas of obesity, resistance to antibiotics and greenhouse gas emissions. The team is united by the desire to use biotechnical innovations to help as many people as possible create a better future for themselves.

Further information about Zaluvida: www.zaluvida.com